Poppers can also decrease sensations of pain, so if you’re having multiple rounds of sex and develop a tear or cut - which increases your risk of contracting an STI if you’re not using a condom or other barrier - you may not notice. This could cause you to do things you wouldn’t normally do, like have sex without using a barrier method to reduce your risk of sexually transmitted infections (STIs). Remember, poppers lower your inhibitions. Same goes for blood pressure medications. Used together, poppers and ED medications can lead to stroke, heart attack, or death. Like poppers, these medications cause a drop in blood pressure. Poppers can interact with other drugs, particularly medications used for erectile dysfunction (ED), such as sildenafil (Viagra) or tadalafil (Cialis). There have been reports of people experiencing permanent eye damage after inhaling certain brands of poppers, particularly those containing isopropyl nitrite. If some does get on your skin, you might experience a chemical burn. Poppers are highly flammable substances that should be kept away from your skin. Here’s a closer look at some of the risks that come with using poppers: Poppers carry a low risk of dependence and addiction, but that doesn’t mean they’re totally safe to use.
